Related literature listed

 

Comments

  1. 海洋食品February 27, 2023 at 1:41 AM

    微流控芯片不是传统意义上的芯片。 它是在微观层面控制流体的技术。 微流控芯片作为新兴的生物芯片，融合了多个学科，包括生理学、病理学、细胞生物学、生物物理学、工程力学、机械设计、材料科学等。 近三十年来，微流控芯片的应用在癌症治疗领域展现出巨大的前景。 可以在微流控芯片上进行各种类型的细胞和组织培养，包括 2D 细胞培养、3D 细胞培养和组织类器官培养。 患者来源的癌细胞和组织可以在微流控芯片上以可视、可控、高通量的方式培养，极大地推进了个体化医疗的进程。 此外，由于可定制性，微流控芯片的功能正在大大扩展。 在这篇综述中，我们介绍了它在开发癌症临床前模型、检测癌症生物标志物、筛选抗癌药物、探索肿瘤异质性和制备纳米药物方面的应用。 着重介绍微流控芯片的功能和最新进展，为推进癌症诊疗提供参考。

    ReplyDelete

Post a Comment

Popular posts from this blog

  GDNF (Glial cell line-derived neurotrophic factor) is a member of the transforming growth factor-beta superfamily, GDNF was was first recognized from glial cells for the ability to protect dopaminergic neurons in the midbrain (Engele et al., 1991; Lin et al., 1993), GDNF is also for ENS (Enteric Nervous System). At current it is known that overexpression, or abnormal expression of GDNF cause brain tumor, hirschsprung disease and especially related to neurocognitive functions (schizophrenia) and tendency of habit, for example GDNF has been regarded as potential common addiction-related gene (for instance, drug use, alcohol abuse, etc.). This is probably because GDNF is expressed in brain and other neuron cells. When analyzing the GDNF interaction with other genes at https://genemania.org/ , for instance with PTGS2 (or COX-2, an enzyme for prostaglandins): https://genemania.org/search/homo-sapiens/GDNF/PTGS2, then I got a quick idea, just wonder if these gene network could be conve...
Read more